Our new Clear+ tissue clearing method is the sole strategy that delipidates samples without improve in morphology and with minimal impact on structural integrity.

Megatome is actually a vibrating microtome built to section a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue harm and data decline.

Request a estimate or demo Uniformly area massive tissues & sample arrays Megatome is the one microtome which can section samples as large as intact nonhuman primate and human organs, which makes it priceless for fields for instance neuropathology.

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SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,

Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them totally clear. This allows mild penetration in to the sample and ensures the acquisition of significant-resolution, in-emphasis picture data.

Megatome is actually a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue damage and data loss.

It’s time for you to enhance your microtome to Megatome. With correct high-frequency slicing for an unmatched choice of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various applications.

The SmartSPIM gentle sheet microscope offers unparalleled resolution and acquisition velocity all through intact tissue volumes, though its modular design and style helps you to update and customise personal factors.

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Protect avoids the variability of hydrogel embedding megatomi.com and the information reduction from PFA preservation, shielding specimens for multiple rounds of processing.

Leverage the Apparent+ tissue clearing method, in addition to eFLASH and patented stochastic electrotransport systems, to promptly apparent and label whole organs. Crucial highlights and characteristics include things like:

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